Recurrence of Tuberculosis Poses Significant Challenge for TB Control: Study Highlights Urgent Need for Action.

Recurrence of Tuberculosis Poses Significant Challenge for TB Control: Study Highlights Urgent Need for Action


Press Note:

Tuberculosis (TB) remains a formidable global health threat, with millions of lives affected each year. A recent study conducted by esteemed medical professionals from GTB Hospitals Sewri, Mumbai, sheds light on the alarming recurrence of TB, posing a significant hurdle for TB control efforts.

The study, led by Dr. Rajendra Tatu Nanavare, Chest Physician, along with a team of dedicated medical experts including Dr. Mrs. Namrata Kaur Bhui, Dr. Shashikant R. Gangawane, Dr. Surabhi Chourasiya, and Dr. Niytanand Maurya, underscores the gravity of recurrent TB cases in India, a country bearing a substantial burden of the disease.

Recurrence of TB occurs when patients previously treated for TB develop a new episode of the disease, either due to relapse or reinfection. This phenomenon is associated with poor treatment outcomes and higher mortality rates, exacerbating the challenges in TB control.

The study highlights key findings, including the prevalence of recurrent TB cases among patients who have completed standard treatment regimens. Factors such as comorbid conditions like HIV/AIDS, uncontrolled diabetes, and drug resistance further complicate the management of TB recurrence.

Dr. Rajendra Tatu Nanavare emphasizes, "Distinguishing between recurrence due to endogenous reactivation or exogenous reinfection is crucial for effective treatment strategies and epidemiological surveillance."

The study also underscores the urgent need for comprehensive preventive measures to curb the recurrence of TB. This includes ensuring the completion of appropriate treatment, early detection of drug resistance through molecular tests like GenXpert, and implementing infection control measures to reduce transmission in clinical and community settings.

Dr. Rajendra Tatu Nanavare adds, "Preventive interventions such as secondary preventive therapy with Isoniazid and scaling up of ART for HIV-positive patients play a vital role in reducing TB recurrence."

The study advocates for increased investments, multi-sectoral action, and the development of new diagnostics, drugs, and vaccines to combat TB effectively. It calls upon policymakers and stakeholders to prioritize TB control efforts and restore access to essential TB services.

In conclusion, the study underscores that early diagnosis, appropriate treatment, and vigilant monitoring are imperative to prevent the recurrence of TB disease. Addressing the underlying risk factors and implementing evidence-based interventions are paramount in achieving the goal of TB elimination.


Regards and Thanks,
Dr. (Prof)Rajendra T. Nanavare
Chest Physician, Mumbai.

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